A type of intelligent nanogel was prepared, which was sensitive to temperature. The nanogels were composed by N-isopropylacrylamide. The optimization of the systhetic conditions by a modified soap-less emulsion polymerization was also studied. We focused on the diameter size controlling, intelligent properties of temperature sensitivity, morphologic characterization and microstructure of nanogel network. Higher poly-dispersivity and smaller particles can be achieved in the system initiated by light compared to the thermal initiation.

The preparation technique of SLN was employed to prepare oral solution of SM-SLN. Mean diameter of products is from 100nm to 200nm, entrapment efficiency is above 90% and drug loading is about 10%. To take Legalon 140 capsules and Yigan Ling Pian as reference preparations, the relative bioavailability of Oral preparations of SM-SLN were 199%(Legalon as reference) ,258%(Yigan Ling Pian as reference) respectively. In addition, the preparation methods of oral solution of SM-SLN were simple which will be convenient to scale-up.

This kind of novel organic-inorganic nanocomposite antimicrobial was prepared by nanocomposite technique. It was proved to have strong antimicrobial activities against several deleterious microorganisms such as Escherichia coli, Bacillus cereus, Staphylococcus aurcus and so on, longer functional times, lower toxicity and cost.

Nano silver particle modified and supported inorganic porous absorptive composite material can be applied in air purification and humidity control. It can be applied in indoor environmental protection and treatment Crystal Wooden Floor Protector that has been exported to Taiwan and Crystal Bactericidal Desiccant that gained a lot of attentions in Japan.

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